35 micrometers!
The cells on the surface of human skin are flat, dead cells called corneocytes, and each is about 35 micrometers across. A micrometer is a millionth of a meter. They are also very thin, about 1 micrometer or less, so each one is shaped like a tiny tile. Living skin cells deeper down are a different shape.
The size is the width of one surface cell, seen from above. Studies describe corneocytes as about 30–50 micrometers across, with an average area of about 1,000 square micrometers. A circle with that area would be 36 micrometers wide, close to the 35 micrometers shown here.
Size varies over the body. Measured by area, cells from the cheek average about 590 square micrometers, which is the area of a circle about 27 micrometers wide. Cells from the abdomen average 1,050–1,240 square micrometers, like circles 37–40 micrometers wide. Face cells are smaller than forearm cells, and the face also replaces its outer layer about twice as fast as the forearm does.
The outer layer of skin, the epidermis, is made of stacked layers of cells. At its base is a single layer of box-shaped stem cells that keep dividing. The new cells are pushed up toward the surface. On the way they fill with keratin, the tough protein that also gives hair and nails their hardness, and they grow flatter.
By the time they reach the top layer, the stratum corneum, the cells are dead. This layer is usually 15–30 cells deep and about 10–20 micrometers thick. It keeps germs out, keeps water in and protects the living layers underneath from rubbing and scraping.
Cells at the surface are shed regularly and replaced by cells from below. The whole top layer is replaced in about four weeks.